Reduced SNAP‐25 alters short‐term plasticity at developing glutamatergic synapses
نویسندگان
چکیده
منابع مشابه
Reduced SNAP-25 alters short-term plasticity at developing glutamatergic synapses.
SNAP-25 is a key component of the synaptic-vesicle fusion machinery, involved in several psychiatric diseases including schizophrenia and ADHD. SNAP-25 protein expression is lower in different brain areas of schizophrenic patients and in ADHD mouse models. How the reduced expression of SNAP-25 alters the properties of synaptic transmission, leading to a pathological phenotype, is unknown. We sh...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2013
ISSN: 1469-221X,1469-3178
DOI: 10.1038/embor.2013.75